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80 Scientific Studies on the Harmful Environmental and Health Effects of Pesticides


Toxicant and Disease Database: The CHE Toxicant and Disease Database is a searchable database that summarizes links between chemical contaminants and approximately 180 human diseases or conditions.

Role of Paraoxonase (PON1) Status in Pesticide Sensitivity: Genetic and Temporal Determinants

Myths of Safe Pesticides

A Small Dose of Toxicology: The Health Effects of Common Chemicals, 2nd edition, by Steven G. Gilbert explores the principles of toxicology by examining the health effects of common chemical agents.

Study of rural New York State Homes finds Pesticides in every sample tested

Pesticides in Ambient Air in Alberta

The unsteady state and inertia of chemical regulation under the US Toxic Substances Control Act

Pesticide risk assessments seen as biased, experts advise

A searchable database of MSDS (material safety data sheets) and product labels at a company called Crop Data Management Systems, Inc:

From Wikipedia on MSDS:

Annual Pesticide Use Maps: 1992-2012 ("Select a pesticide." There are MANY to pick from.)

County-level pesticide use estimates are available in tabular format

(USGS) Estimated Annual Agricultural Pesticide Use for Counties of the Conterminous United States, 2008–12 (report available in pdf format)

THE PPDB Pesticide Properties Database is a comprehensive relational database of pesticide chemical identity, physicochemical, human health, and ecotoxicological data.

(USGS) Pesticides in U.S. Streams and Rivers: Occurrence and Trends during 1992-2011

-- (USGS) Pesticide National Synthesis Project

-- (USGS) Estimation of Annual Agricultural Pesticide Use for Counties of the Conterminous United States, 1992–2009 (report available in pdf format)

-- (USGS) Pesticide Use Maps - Glyphosate

-- The Mind, Disrupted Biomonitoring Project - "In 2009, 12 leaders and self-advocates from the learning and developmental disabilities community volunteered to have their bodies tested for 89 chemicals known or suspected of being neurodevelopmental toxicants or endocrine disruptors, including bisphenol A, lead, mercury, organochlorine pesticides, polybrominated diphenyl ethers (PBDEs), perchlorate, perfluorinated compounds (PFCs), and triclosan. 61 chemicals (out of 89 tested) were found in the twelve participants. Each participant was found to harbor at least 26 and as many as 38 of the tested chemicals in their bodies. Sixteen chemicals were detected in every participant." More at

-- (Press release 25 Feb 2015) Agricultural insecticides pose a global risk to surface water bodies - The first global map to be produced on potential insecticide contamination: Leipzig/ Landau. Streams within approx. 40% of the global land surface is at risk from applying insecticides. These were the results from the first global map to be modeled on insecticide runoff to surface waters, which has just been published in the journal Environmental Pollution by researchers from the Helmholtz Center for Environmental Research (UFZ) and the University of Koblenz-Landau together with the University of Milan, Aarhus University and Aachen University. According to the publication, particularly streams in the Mediterranean, the USA, Central America, and Southeast Asia are at risk.

-- Agricultural insecticides threaten surface waters on a global scale (Sebastian Stehle and Ralf Schulz), Institute for Environmental Sciences, University Koblenz-Landau, D-76829 Landau, Germany. Edited by Jules M. Blais, University of Ottawa, Ottawa, Canada, and accepted by the Editorial Board March 13, 2015 (received for review January 6, 2015)**

PDF of the report from NY State Atty General on the problems with 'inert' ingredients in pesticides

Exposure and Interaction – The Potential Health Impacts of Using Multiple Pesticides: A Case Study of Three Commonly Used Fumigants.

Research finds that low concentrations of pesticides can become a toxic mixture

Unexamined Endocrine Disruption? Pesticides Inhibit Prostaglandin Activity

Pesticides and the Immune System of urban-use pesticides to streams likely impairs invertebrate assemblages

Rheumatoid Arthritis in Agricultural Health Study Spouses: Associations with Pesticides and Other Farm Exposures

National Marine Fisheries Service Endangered Species Act Section 7 Consultation Biological Opinion on Environmental Protection Agency Registration of Pesticides Containing Azinphos methyl, Bensulide, Dimethoate, Disulfoton, Ethoprop, Fenamiphos, Naled, Methamidophos, Methidathion, Methyl parathion, Phorate, and Phosmet

US G.A.O. Lawn Care Pesticides: Risks Remain Uncertain While Prohibited Safety Claims Continue - not peer-reviewed science, or data but helpful info regarding safety claims and legal aspects of.

Chemicals In Our Waters Are Affecting Humans And Aquatic Life In Unanticipated Ways

Increasing Use of Pyrethroids in Canadian Households: Should We Be Concerned?

Accumulation levels and characteristics of some pesticides in human adipose tissue samples from Southeast China (mortality of malignant tumors tends to associate with the pesticides levels in human adipose tissue [fat].)

Effect of Endocrine Disruptor Pesticides: A Review!po=6.25000

Pest Smart app to look up pesticide names

Common insecticides mimic melatonin, creating a higher potential risk for diabetes and metabolic diseases

DISEASES linked to PESTICIDES (grouped by the strength of evidence) - good site with lots of info (

Scientists identify six important shortcomings in the current procedures used to assess pesticide safety

Toxic Mixtures in Time—The Sequence Makes the Poison (sequence of exposures affect toxicity)

Effects of pesticide mixtures in human and animal models: An update of the recent literature

Endocrine-disrupting chemicals (EDCs) deplete glutathione (an important detoxifying antioxidant) leading to worsening inflammation in airways of mice (asthma)

Pyrethroid concentrations and persistence following indoor application - 70% of cypermethrin, a pyrethroid pesticide found in up to 90% of homes, still found in dust samples around the house after one year

Occupational pesticide exposure linked to fixed airflow obstruction and chronic bronchitis

Neonics exhibiting endocrine disruption - effects of neonicotinoids on aromatase (enzyme that produces estrogen) activity and hormone production

Toxicity of formulants and heavy metals in glyphosate-based herbicides and other pesticides

Ignoring Adjuvant Toxicity Falsifies the Safety Profile of Commercial Pesticides

The Lancet Commission on pollution and health

2008–2009 Annual Report - President’s Cancer Panel REDUCING ENVIRONMENTAL CANCER RISK What We Can Do Now

Commercial pesticides: Not as safe as they seem

Nonmonotonic Dose-Response Curves Occur in Dose Ranges That Are Relevant to Regulatory Decision-Making

Flaws in industry-funded pesticide evaluation.

Pesticide residue builds up in soil - European study

Stronger pesticide regulations are likely needed to protect all bee species, say studies:

Pesticide exposure raises the risk for cardiovascular disease among Latino workers:

Advancements in Life Cycle Human Exposure and Toxicity Characterization:

Pesticide exposure contributes to faster ALS progression:

California state and county officials falling short in evaluating the use of agricultural pesticides:

Chemical mixtures pose an ‘underestimated’ risk to human health, says, scientists:

The USA lags behind other agricultural nations in banning harmful pesticides:

Biting backfire: Some mosquitoes actually benefit from pesticide application:

Pesticide Exposure Linked to Teen Depression in Agricultural Communities:

Three billion birds have been lost in North America since 1970

45% higher risk of heart disease or stroke in those with high pesticide exposure (pesticide applicators at risk):

Common Fungicides’ Use Leads To Algae Blooms:

Pesticide companies leverage regulations for financial gains

School of Medicine and Health Sciences report outlining information for physicians to help patients avoid and lessen exposure to pesticides, lead, and mercury, associated with brain development and pregnancy complications.

Researchers develop a model for a more realistic risk assessment of pesticides:

Long-Term Insecticide Exposure Tied to Heart Disease - Pyrethroids in mosquito repellents, pet sprays, and lice shampoos may increase cardiovascular risks:

Association of urinary metabolites of organophosphate and pyrethroid insecticides and phenoxy herbicides with endometriosis:

Pesticide testing is flawed—and it’s harming our birds and bees:

The association between pesticide use and cutaneous melanoma: A systematic review and meta‐analysis:

Persistent organic pollutant exposure and celiac disease: A pilot study:

Environmental contaminants alter the gut microbiome, health

"Chemicals such as bisphenols, phthalates, some pesticides, persistent organic pollutants, and heavy metals can alter hormone metabolism and are associated with adverse health outcomes."

Milkweed, the only food source for monarch caterpillars, is ubiquitously contaminated

64 pesticide residues were found in milkweed, the west's main food for monarch butterflies. Milkweed samples from all locations studied in California’s Central Valley were contaminated with pesticides, sometimes at levels harmful to monarchs and other insects.

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